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6 Module 6: Discussion and Implications

Carlos C. Goller

Module Overview

In this module, we will use our knowledge of the methods to analyze the second set of figures from this study. You will work with groups to carefully and systematically analyze each figure, identifying the controls, readout, findings, and implications of this work. We will think critically about the data and assumptions made, connecting these results to the previous set of figures.

Module Learning Objectives

Learning Outcomes

By the end of this module, you should be able to:

  • Discuss the findings of this study with peers
  • Summarize the results, implications, and discussion in text and as a concept map
  • Integrate the findings of the study with the methods used and claims made
  • Situate the findings of the paper within the field of study

Module To-Do List

Module To Do List

During this module, you will complete the following items:

  • Review the information provided in our Delftia Book before our first session for this module.
  • Complete the in-class activity and submit it individually before the end of this module.
  • Create a summary of the entire article and a concept map before the end of this module.
  • Write your own discussion for the article.

Return to the Article and Focus on the Results and Implications

Review the figures of this published peer-reviewed article and consider the claims the authors made. Remember that this study was published in the prestigious scientific journal Science. Also, download and review the Supplementary Materials.

Huang, Wei, Janneth Rodrigues, Etienne Bilgo, José R. Tormo, Joseph D. Challenger, Cristina D. Cozar-Gallardo, Ignacio Pérez-Victoria et al. “Delftia Tsuruhatensis TC1 Symbiont Suppresses Malaria Transmission by Anopheline Mosquitoes.” Science, (2023). Accessed September 8, 2025. https://doi.org/adf8141.

What were the main findings of this study?

Exercises

Summarize the main findings and implications of this study.

  • What did the authors claim in the introduction?
  • Are the results convincing? Why or why not?
  • How will these findings impact the field and future studies?

Why are these findings important?

What is the evidence?

Returning to the C.R.E.A.T.E. Approach

The C.R.E.A.T.E. approach is a pedagogical method for reading scientific primary literature that focuses on active learning and critical thinking. Developed by biologist Sally G. Hoskins, it encourages students to engage with research papers as scientists do, by analyzing data, questioning conclusions, and designing follow-up experiments. 
The acronym C.R.E.A.T.E. stands for five core steps: 
  • C – Consider: Before reading the article, we analyze the title, authors, and abstract to formulate a preliminary idea of the study. We then create a concept map or draw a diagram of what they already know about the topic, listing any unfamiliar terms.
  • R – Read: We read the full article, paying close attention to the details of the experimental setup and methods. We define unfamiliar vocabulary and create drawings or flowcharts to visualize the experimental design.
  • E – Elucidate the hypotheses: We identify the specific research questions and hypotheses that the study aims to address. This involves a critical comparison of the paper’s stated hypotheses with the actual outcomes and results.
  • A – Analyze and interpret the data: This is a key step where scholars intensely scrutinize the figures and data tables. They analyze the results to form their own interpretation, comparing it with the authors’ conclusions.
  • T – Think of the next Experiment: Based on their understanding of the article, scholars propose new, related experiments that could logically follow the study. They may debate these ideas in a “grant panel” style exercise with peers, which highlights the creative and open-ended nature of scientific research. 
The C.R.E.A.T.E. method is designed to demystify the scientific process and build students’ confidence in reading complex research. It has been demonstrated to enhance critical thinking skills, alter students’ attitudes toward science and research, and improve their understanding of how knowledge is constructed. 

 

Exercise

Consider the C.R.E.A.T.E. method and what you know about the study.  If you were to write a brief discussion of the article, what would you state? Why?

Reflect

References

Huang, Wei, Janneth Rodrigues, Etienne Bilgo, José R. Tormo, Joseph D. Challenger, Cristina D. Cozar-Gallardo, Ignacio Pérez-Victoria et al. “Delftia Tsuruhatensis TC1 Symbiont Suppresses Malaria Transmission by Anopheline Mosquitoes.” Science, (2023). Accessed September 10, 2025. https://doi.org/adf8141.

 

License

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Module 6: Discussion and Implications Copyright © 2025 by Carlos C. Goller is licensed under a Creative Commons Attribution 4.0 International License, except where otherwise noted.