3 Current State of the Art
- Technological Advancements
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- Discuss any recent developments in the technology since the TED talk.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180073/This article was published in 2022. It mentions some applications of the body parts on a chip.
- Organ/Disease Modelling: highlights the use of OOAC technology to model diseases associated with different organs (A 3D retina organoid model for studying X-linked retinitis pigmentosa and its impact on blindness; Vitro models of cardiomyopathy and myocardial failure, used to study diseases like Barth syndrome and cardiac hypertrophy respectively, which are useful for drug discovery and functional genetic studies.)
- Dentistry: Focusing on oral health, the section describes innovations such as the tooth-on-a-chip and oral mucosa-on-a-chip models. These devices simulate the oral environment to study interactions between dental materials and oral tissues. The tooth-on-a-chip is used to analyze the responses of dental pulp cells to biomaterials, while the oral mucosa-on-a-chip assesses mucosal remodeling and responses to both dental materials and oral bacteria.
- Evaluate the current commercial availability and any barriers to market entry.
- Companies and academic institutions can using these models for drug screening, disease modeling, and toxicity testing.
- Discuss any recent developments in the technology since the TED talk.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9180073/This article was published in 2022. It mentions some applications of the body parts on a chip.
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