Key Terms

• alkylamine
• amine
• arylamine
• azo compound (R–N=N–R′)
• Curtius rearrangement
• Gabriel amine synthesis
• heterocyclic amine
• Hofmann elimination reaction
• Hofmann rearrangement
• imide (O=C–N–C=O)
• primary amine (RNH₂)
• quaternary ammonium salt
• reductive amination
• Sandmeyer reaction
• secondary amine (R₂NH)
• tertiary amine (R₃N)

Summary of Reactions 12

• Synthesis of amines (Section 12.4)
• Reduction of nitriles

• Reduction of amides

• Reduction of nitrobenzenes

• S_N2 Alkylation of alkyl halides

• Reduction of azides

• Reductive amination of aldehydes/ketones

Reactions of amines

• Alkylation with alkyl halides
• Acylation of acyl chlorides